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Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones

Histones are essential elements of chromatin structure and gene regulation in eukaryotes. An unexpected attribute of these nuclear proteins is their antimicrobial activity. A framework for histone release and function in host defense in vivo was revealed with the discovery of neutrophil extracellula...

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Detalles Bibliográficos
Autores principales: Döhrmann, Simon, LaRock, Christopher N., Anderson, Ericka L., Cole, Jason N., Ryali, Brinda, Stewart, Chelsea, Nonejuie, Poochit, Pogliano, Joe, Corriden, Ross, Ghosh, Partho, Nizet, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318940/
https://www.ncbi.nlm.nih.gov/pubmed/28220899
http://dx.doi.org/10.1038/srep43039