Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III

Enhanced mitochondrial stability and decreased dependence on oxidative phosphorylation confer an acquired resistance to apoptosis in cancer cells, but may present opportunities for therapeutic intervention. The compound pancratistatin (PST) has been shown to selectively induce apoptosis in cancer ce...

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Detalles Bibliográficos
Autores principales: Ma, Dennis, Pignanelli, Christopher, Tarade, Daniel, Gilbert, Tyler, Noel, Megan, Mansour, Fadi, Adams, Scott, Dowhayko, Alexander, Stokes, Kyle, Vshyvenko, Sergey, Hudlicky, Tomas, McNulty, James, Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318952/
https://www.ncbi.nlm.nih.gov/pubmed/28220885
http://dx.doi.org/10.1038/srep42957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318952/
https://www.ncbi.nlm.nih.gov/pubmed/28220885
http://dx.doi.org/10.1038/srep42957

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