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A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse

Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned during later embryogenesis, the role of Gsc in the organizer has remained enigmatic. Using conditional gain-of-function approaches in Xenopus and mouse to maintain Gsc expre...

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Detalles Bibliográficos
Autores principales: Ulmer, Bärbel, Tingler, Melanie, Kurz, Sabrina, Maerker, Markus, Andre, Philipp, Mönch, Dina, Campione, Marina, Deißler, Kirsten, Lewandoski, Mark, Thumberger, Thomas, Schweickert, Axel, Fainsod, Abraham, Steinbeißer, Herbert, Blum, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318956/
https://www.ncbi.nlm.nih.gov/pubmed/28220837
http://dx.doi.org/10.1038/srep43010