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A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
Goosecoid (Gsc) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned during later embryogenesis, the role of Gsc in the organizer has remained enigmatic. Using conditional gain-of-function approaches in Xenopus and mouse to maintain Gsc expre...
Autores principales: | Ulmer, Bärbel, Tingler, Melanie, Kurz, Sabrina, Maerker, Markus, Andre, Philipp, Mönch, Dina, Campione, Marina, Deißler, Kirsten, Lewandoski, Mark, Thumberger, Thomas, Schweickert, Axel, Fainsod, Abraham, Steinbeißer, Herbert, Blum, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318956/ https://www.ncbi.nlm.nih.gov/pubmed/28220837 http://dx.doi.org/10.1038/srep43010 |
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