Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease – UMOD (ADTKD-UMOD)

‘Autosomal dominant tubulointerstitial kidney disease – UMOD’ (ADTKD-UMOD) is caused by impaired maturation and secretion of mutant uromodulin (UMOD) in thick ascending limb of Henle loop (TAL) cells, resulting in endoplasmic reticulum (ER) stress and unfolded protein response (UPR). To gain insight...

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Detalles Bibliográficos
Autores principales: Kemter, Elisabeth, Fröhlich, Thomas, Arnold, Georg J., Wolf , Eckhard, Wanke, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318959/
https://www.ncbi.nlm.nih.gov/pubmed/28220896
http://dx.doi.org/10.1038/srep42970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318959/
https://www.ncbi.nlm.nih.gov/pubmed/28220896
http://dx.doi.org/10.1038/srep42970

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