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Giving AXL the axe: targeting AXL in human malignancy

The receptor tyrosine kinase AXL, activated by a complex interaction between its ligand growth arrest-specific protein 6 and phosphatidylserine, regulates various vital cellular processes, including proliferation, survival, motility, and immunologic response. Although not implicated as an oncogenic...

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Detalles Bibliográficos
Autores principales: Gay, Carl M, Balaji, Kavitha, Byers, Lauren Averett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318970/
https://www.ncbi.nlm.nih.gov/pubmed/28072762
http://dx.doi.org/10.1038/bjc.2016.428