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Giving AXL the axe: targeting AXL in human malignancy
The receptor tyrosine kinase AXL, activated by a complex interaction between its ligand growth arrest-specific protein 6 and phosphatidylserine, regulates various vital cellular processes, including proliferation, survival, motility, and immunologic response. Although not implicated as an oncogenic...
Autores principales: | Gay, Carl M, Balaji, Kavitha, Byers, Lauren Averett |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318970/ https://www.ncbi.nlm.nih.gov/pubmed/28072762 http://dx.doi.org/10.1038/bjc.2016.428 |
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