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RNAs competing for microRNAs mutually influence their fluctuations in a highly non-linear microRNA-dependent manner in single cells

BACKGROUND: Distinct RNA species may compete for binding to microRNAs (miRNAs). This competition creates an indirect interaction between miRNA targets, which behave as miRNA sponges and eventually influence each other’s expression levels. Theoretical predictions suggest that not only the mean expres...

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Detalles Bibliográficos
Autores principales: Bosia, Carla, Sgrò, Francesco, Conti, Laura, Baldassi, Carlo, Brusa, Davide, Cavallo, Federica, Cunto, Ferdinando Di, Turco, Emilia, Pagnani, Andrea, Zecchina, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319025/
https://www.ncbi.nlm.nih.gov/pubmed/28219439
http://dx.doi.org/10.1186/s13059-017-1162-x