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A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

BACKGROUND: Expression quantitative trait loci (eQTL) databases represent a valuable resource to link disease-associated SNPs to specific candidate genes whose gene expression is significantly modulated by the SNP under investigation. We previously identified signal inhibitory receptor on leukocytes...

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Detalles Bibliográficos
Autores principales: Kumar, Dilip, Puan, Kia Joo, Andiappan, Anand Kumar, Lee, Bernett, Westerlaken, Geertje H. A., Haase, Doreen, Melchiotti, Rossella, Li, Zhuang, Yusof, Nurhashikin, Lum, Josephine, Koh, Geraldine, Foo, Shihui, Yeong, Joe, Alves, Alexessander Couto, Pekkanen, Juha, Sun, Liang Dan, Irwanto, Astrid, Fairfax, Benjamin P., Naranbhai, Vivek, Common, John E. A., Tang, Mark, Chuang, Chin Keh, Jarvelin, Marjo-Riitta, Knight, Julian C., Zhang, Xuejun, Chew, Fook Tim, Prabhakar, Shyam, Jianjun, Liu, Wang, De Yun, Zolezzi, Francesca, Poidinger, Michael, Lane, E. Birgitte, Meyaard, Linde, Rötzschke, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319034/
https://www.ncbi.nlm.nih.gov/pubmed/28219444
http://dx.doi.org/10.1186/s13073-017-0404-6