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Microglia P2Y6 receptor is related to Parkinson’s disease through neuroinflammatory process

BACKGROUND: Microglia in the central nervous system (CNS) were reported to play crucial role in neurodegeneration. Previous studies showed that P2Y6 receptor (P2Y6R) mainly contributed to microglia activation and phagocytosis in CNS. However, the level of P2Y6R in Parkinson’s disease (PD) patients i...

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Detalles Bibliográficos
Autores principales: Yang, Xiaodong, Lou, Yue, Liu, Guidong, Wang, Xueping, Qian, Yiwei, Ding, Jianqing, Chen, Shengdi, Xiao, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319038/
https://www.ncbi.nlm.nih.gov/pubmed/28219441
http://dx.doi.org/10.1186/s12974-017-0795-8