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Computing structure-based lipid accessibility of membrane proteins with mp_lipid_acc in RosettaMP

BACKGROUND: Membrane proteins are underrepresented in structural databases, which has led to a lack of computational tools and the corresponding inappropriate use of tools designed for soluble proteins. For membrane proteins, lipid accessibility is an essential property. Although programs are availa...

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Detalles Bibliográficos
Autores principales: Koehler Leman, Julia, Lyskov, Sergey, Bonneau, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319049/
https://www.ncbi.nlm.nih.gov/pubmed/28219343
http://dx.doi.org/10.1186/s12859-017-1541-z