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Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice

BACKGROUND: In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual way. Appropriate analysis of the data from both arms of the study allows invest...

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Detalles Bibliográficos
Autores principales: Walter, Stephen D., Turner, Robin M., Macaskill, Petra, McCaffery, Kirsten J., Irwig, Les
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319089/
https://www.ncbi.nlm.nih.gov/pubmed/28219326
http://dx.doi.org/10.1186/s12874-017-0304-x