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PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

BACKGROUND: Defining how epigenetic information is established in the germline during fetal development is key to understanding how epigenetic information is inherited and impacts on evolution and human health and disease. RESULTS: Here, we show that Polycomb Repressive Complex 2 is transiently loca...

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Detalles Bibliográficos
Autores principales: Prokopuk, Lexie, Stringer, Jessica M., Hogg, Kirsten, Elgass, Kirstin D., Western, Patrick S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319108/
https://www.ncbi.nlm.nih.gov/pubmed/28239420
http://dx.doi.org/10.1186/s13072-017-0113-9