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PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells
BACKGROUND: Defining how epigenetic information is established in the germline during fetal development is key to understanding how epigenetic information is inherited and impacts on evolution and human health and disease. RESULTS: Here, we show that Polycomb Repressive Complex 2 is transiently loca...
Autores principales: | Prokopuk, Lexie, Stringer, Jessica M., Hogg, Kirsten, Elgass, Kirstin D., Western, Patrick S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319108/ https://www.ncbi.nlm.nih.gov/pubmed/28239420 http://dx.doi.org/10.1186/s13072-017-0113-9 |
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