Clarithromycin attenuates IL-13–induced periostin production in human lung fibroblasts

BACKGROUND: Periostin is a biomarker indicating the presence of type 2 inflammation and submucosal fibrosis; serum periostin levels have been associated with asthma severity. Macrolides have immunomodulatory effects and are considered a potential therapy for patients with severe asthma. Therefore, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Komiya, Kosaku, Ohta, Shoichiro, Arima, Kazuhiko, Ogawa, Masahiro, Suzuki, Shoichi, Mitamura, Yasutaka, Nunomura, Satoshi, Nanri, Yasuhiro, Yoshihara, Tomohito, Kawaguchi, Atsushi, Kadota, Jun-ichi, Rubin, Bruce K., Izuhara, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319114/
https://www.ncbi.nlm.nih.gov/pubmed/28219384
http://dx.doi.org/10.1186/s12931-017-0519-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319114/
https://www.ncbi.nlm.nih.gov/pubmed/28219384
http://dx.doi.org/10.1186/s12931-017-0519-8

Ejemplares similares