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Clarithromycin attenuates IL-13–induced periostin production in human lung fibroblasts
BACKGROUND: Periostin is a biomarker indicating the presence of type 2 inflammation and submucosal fibrosis; serum periostin levels have been associated with asthma severity. Macrolides have immunomodulatory effects and are considered a potential therapy for patients with severe asthma. Therefore, w...
Autores principales: | Komiya, Kosaku, Ohta, Shoichiro, Arima, Kazuhiko, Ogawa, Masahiro, Suzuki, Shoichi, Mitamura, Yasutaka, Nunomura, Satoshi, Nanri, Yasuhiro, Yoshihara, Tomohito, Kawaguchi, Atsushi, Kadota, Jun-ichi, Rubin, Bruce K., Izuhara, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319114/ https://www.ncbi.nlm.nih.gov/pubmed/28219384 http://dx.doi.org/10.1186/s12931-017-0519-8 |
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