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Kynurenine pathway metabolism and neuroinflammatory disease

Immune-mediated activation of tryptophan (TRYP) catabolism via the kynurenine pathway (KP) is a consistent finding in all inflammatory disorders. Several studies by our group and others have examined the neurotoxic potential of neuroreactive TRYP metabolites, including quinolinic acid (QUIN) in neur...

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Detalles Bibliográficos
Autores principales: Braidy, Nady, Grant, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319230/
https://www.ncbi.nlm.nih.gov/pubmed/28250737
http://dx.doi.org/10.4103/1673-5374.198971