Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

Formation of amyloid fibrils underlies a wide range of human disorders, including Alzheimer's and prion diseases. The amyloid fibrils can be readily detected thanks to thioflavin T (ThT), a small molecule that gives strong fluorescence upon binding to amyloids. Using the amyloid fibrils of Aβ40...

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Detalles Bibliográficos
Autores principales: Xue, Christine, Lin, Tiffany Yuwen, Chang, Dennis, Guo, Zhefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Biochemistry and Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319338/
https://www.ncbi.nlm.nih.gov/pubmed/28280572
http://dx.doi.org/10.1098/rsos.160696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319338/
https://www.ncbi.nlm.nih.gov/pubmed/28280572
http://dx.doi.org/10.1098/rsos.160696

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