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Mfn1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion

Mitochondria are double-membrane organelles with varying shapes influenced by metabolic conditions, developmental stage, and environmental stimuli(1–4). Their dynamic morphology is realized through regulated and balanced fusion and fission processes(5, 6). Fusion is crucial for the health and physio...

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Detalles Bibliográficos
Autores principales: Cao, Yu-Lu, Meng, Shuxia, Chen, Yang, Feng, Jian-Xiong, Gu, Dong-Dong, Yu, Bing, Li, Yu-Jie, Yang, Jin-Yu, Liao, Shuang, Chan, David C., Gao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319402/
https://www.ncbi.nlm.nih.gov/pubmed/28114303
http://dx.doi.org/10.1038/nature21077