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Mfn1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion
Mitochondria are double-membrane organelles with varying shapes influenced by metabolic conditions, developmental stage, and environmental stimuli(1–4). Their dynamic morphology is realized through regulated and balanced fusion and fission processes(5, 6). Fusion is crucial for the health and physio...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319402/ https://www.ncbi.nlm.nih.gov/pubmed/28114303 http://dx.doi.org/10.1038/nature21077 |