Cargando…

C-terminally mutated tubby protein accumulates in aggresomes

The tubby protein (Tub), a putative transcription factor, plays important roles in the maintenance and function of neuronal cells. A splicing defect-causing mutation in the 3′-end of the tubby gene, which is predicted to disrupt the carboxy-terminal region of the Tub protein, causes maturity-onset o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sunshin, Sung, Ho Jin, Lee, Ji Won, Kim, Yun Hee, Oh, Yong-Seok, Yoon, Kyong-Ah, Heo, Kyun, Suh, Pann-Ghill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319663/
https://www.ncbi.nlm.nih.gov/pubmed/27697107
http://dx.doi.org/10.5483/BMBRep.2017.50.1.140