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How important is thermodynamics for identifying elementary flux modes?

We present a method for computing thermodynamically feasible elementary flux modes (tEFMs) using equilibrium constants without need of internal metabolite concentrations. The method is compared with the method based on a binary distinction between reversible and irreversible reactions. When all reac...

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Detalles Bibliográficos
Autores principales: Peres, Sabine, Jolicœur, Mario, Moulin, Cécile, Dague, Philippe, Schuster, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319754/
https://www.ncbi.nlm.nih.gov/pubmed/28222104
http://dx.doi.org/10.1371/journal.pone.0171440