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Data-driven reverse engineering of signaling pathways using ensembles of dynamic models
Despite significant efforts and remarkable progress, the inference of signaling networks from experimental data remains very challenging. The problem is particularly difficult when the objective is to obtain a dynamic model capable of predicting the effect of novel perturbations not considered durin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319798/ https://www.ncbi.nlm.nih.gov/pubmed/28166222 http://dx.doi.org/10.1371/journal.pcbi.1005379 |