Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells

A hallmark of pulmonary tuberculosis is the formation of macrophage-rich granulomas. These may restrict Mycobacterium tuberculosis (Mtb) growth, or progress to central necrosis and cavitation, facilitating pathogen growth. To determine factors leading to Mtb proliferation and host cell death, we use...

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Detalles Bibliográficos
Autores principales: Mahamed, Deeqa, Boulle, Mikael, Ganga, Yashica, Mc Arthur, Chanelle, Skroch, Steven, Oom, Lance, Catinas, Oana, Pillay, Kelly, Naicker, Myshnee, Rampersad, Sanisha, Mathonsi, Colisile, Hunter, Jessica, Wong, Emily B, Suleman, Moosa, Sreejit, Gopalkrishna, Pym, Alexander S, Lustig, Gila, Sigal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319838/
https://www.ncbi.nlm.nih.gov/pubmed/28130921
http://dx.doi.org/10.7554/eLife.22028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319838/
https://www.ncbi.nlm.nih.gov/pubmed/28130921
http://dx.doi.org/10.7554/eLife.22028

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