De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones

Squamous cell carcinomas occurring at transition zones are highly malignant tumors with poor prognosis. The identity of the cell population and the signaling pathways involved in the progression of transition zone squamous cell carcinoma are poorly understood, hence representing limited options for...

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Detalles Bibliográficos
Autores principales: McCauley, Heather A, Chevrier, Véronique, Birnbaum, Daniel, Guasch, Géraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319840/
https://www.ncbi.nlm.nih.gov/pubmed/28219480
http://dx.doi.org/10.7554/eLife.22914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319840/
https://www.ncbi.nlm.nih.gov/pubmed/28219480
http://dx.doi.org/10.7554/eLife.22914

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