Cargando…

Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

Sarcomere assembly is a highly orchestrated and dynamic process which adapts, during perinatal development, to accommodate growth of the heart. Sarcomeric components, including titin, undergo an isoform transition to adjust ventricular filling. Many sarcomeric genes have been implicated in congenita...

Descripción completa

Detalles Bibliográficos
Autores principales: Smart, Nicola, Riegler, Johannes, Turtle, Cameron W., Lygate, Craig A., McAndrew, Debra J., Gehmlich, Katja, Dubé, Karina N., Price, Anthony N., Muthurangu, Vivek, Taylor, Andrew M., Lythgoe, Mark F., Redwood, Charles, Riley, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319848/
https://www.ncbi.nlm.nih.gov/pubmed/27914791
http://dx.doi.org/10.1016/j.yjmcc.2016.10.010