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Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting

[Image: see text] Glycoprotein gp120 is a surface antigen and virulence factor of human immunodeficiency virus 1. Broadly neutralizing antibodies (bNAbs) that react to gp120 from a variety of HIV isolates offer hope for the development of broadly effective immunogens for vaccination purposes, if the...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyan, Grant, Oliver C., Ito, Keigo, Wallace, Aaron, Wang, Shixia, Zhao, Peng, Wells, Lance, Lu, Shan, Woods, Robert J., Sharp, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319886/
https://www.ncbi.nlm.nih.gov/pubmed/28102671
http://dx.doi.org/10.1021/acs.biochem.6b00888