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Structural Analysis of the Glycosylated Intact HIV-1 gp120–b12 Antibody Complex Using Hydroxyl Radical Protein Footprinting
[Image: see text] Glycoprotein gp120 is a surface antigen and virulence factor of human immunodeficiency virus 1. Broadly neutralizing antibodies (bNAbs) that react to gp120 from a variety of HIV isolates offer hope for the development of broadly effective immunogens for vaccination purposes, if the...
Autores principales: | Li, Xiaoyan, Grant, Oliver C., Ito, Keigo, Wallace, Aaron, Wang, Shixia, Zhao, Peng, Wells, Lance, Lu, Shan, Woods, Robert J., Sharp, Joshua S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319886/ https://www.ncbi.nlm.nih.gov/pubmed/28102671 http://dx.doi.org/10.1021/acs.biochem.6b00888 |
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