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A novel redox regulator, MnTnBuOE-2-PyP(5+), enhances normal hematopoietic stem/progenitor cell function

The signaling of reactive oxygen species (ROS) is essential for the maintenance of normal cellular function. However, whether and how ROS regulate stem cells are unclear. Here, we demonstrate that, in transgenic mice expressing the human manganese superoxide dismutase (MnSOD) gene, a scavenger of RO...

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Detalles Bibliográficos
Autores principales: Zhao, Y., Carroll, D.W., You, Y., Chaiswing, L., Wen, R., Batinic-Haberle, I., Bondada, S., Liang, Y., St. Clair, D.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320058/
https://www.ncbi.nlm.nih.gov/pubmed/28231483
http://dx.doi.org/10.1016/j.redox.2017.02.005