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Hypoxia-inducible factor 1 mediates hypoxia-enhanced synthesis of progesterone during luteinization of granulosa cells

Hypoxia has been suggested to enhance progesterone (P4) synthesis in luteinizing granulosa cells (GCs), but the mechanism is unclear. The present study was designed to test the hypothesis that the hypoxia-induced increase in P4 synthesis during luteinization in bovine GCs is mediated by hypoxia-indu...

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Detalles Bibliográficos
Autores principales: FADHILLAH, YOSHIOKA, Shin, NISHIMURA, Ryo, YAMAMOTO, Yuki, KIMURA, Koji, OKUDA, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320433/
https://www.ncbi.nlm.nih.gov/pubmed/27840375
http://dx.doi.org/10.1262/jrd.2016-068