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Departure from optimal O(2) level for mouse trophoblast stem cell proliferation and potency leads to most rapid AMPK activation

Previous studies showed that cultured mouse trophoblast stem cells (mTSCs) have the most rapid proliferation, normal maintenance of stemness/potency, the least spontaneous differentiation, and the lowest level of stress-activated protein kinase (SAPK) when incubated at 2% O(2) rather than at the tra...

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Detalles Bibliográficos
Autores principales: YANG, Yu, JIANG, Zhongliang, BOLNICK, Alan, DAI, Jing, PUSCHECK, Elizabeth E, RAPPOLEE, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320434/
https://www.ncbi.nlm.nih.gov/pubmed/27867161
http://dx.doi.org/10.1262/jrd.2016-110