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PVN Blockade of p44/42 MAPK Pathway Attenuates Salt-induced Hypertension through Modulating Neurotransmitters and Attenuating Oxidative Stress

The imbalance of neurotransmitters and excessive oxidative stress responses contribute to the pathogenesis of hypertension. In this study, we determined whether blockade of p44/42 MAPK pathway in the hypothalamic paraventricular nucleus (PVN) ameliorates the development of hypertension through modul...

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Detalles Bibliográficos
Autores principales: Gao, Hong-Li, Yu, Xiao-Jing, Liu, Kai-Li, Shi, Xiao-Lian, Qi, Jie, Chen, Yan-Mei, Zhang, Yan, Bai, Juan, Yi, Qiu-Yue, Feng, Zhi-Peng, Chen, Wen-Sheng, Cui, Wei, Liu, Jin-Jun, Zhu, Guo-Qing, Kang, Yu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320530/
https://www.ncbi.nlm.nih.gov/pubmed/28225041
http://dx.doi.org/10.1038/srep43038