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PVN Blockade of p44/42 MAPK Pathway Attenuates Salt-induced Hypertension through Modulating Neurotransmitters and Attenuating Oxidative Stress
The imbalance of neurotransmitters and excessive oxidative stress responses contribute to the pathogenesis of hypertension. In this study, we determined whether blockade of p44/42 MAPK pathway in the hypothalamic paraventricular nucleus (PVN) ameliorates the development of hypertension through modul...
Autores principales: | Gao, Hong-Li, Yu, Xiao-Jing, Liu, Kai-Li, Shi, Xiao-Lian, Qi, Jie, Chen, Yan-Mei, Zhang, Yan, Bai, Juan, Yi, Qiu-Yue, Feng, Zhi-Peng, Chen, Wen-Sheng, Cui, Wei, Liu, Jin-Jun, Zhu, Guo-Qing, Kang, Yu-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320530/ https://www.ncbi.nlm.nih.gov/pubmed/28225041 http://dx.doi.org/10.1038/srep43038 |
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