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High mutation rates explain low population genetic divergence at copy-number-variable loci in Homo sapiens

Copy-number-variable (CNV) loci differ from single nucleotide polymorphic (SNP) sites in size, mutation rate, and mechanisms of maintenance in natural populations. It is therefore hypothesized that population genetic divergence at CNV loci will differ from that found at SNP sites. Here, we test this...

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Detalles Bibliográficos
Autores principales: Hu, Xin-Sheng, Yeh, Francis C., Hu, Yang, Deng, Li-Ting, Ennos, Richard A., Chen, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320550/
https://www.ncbi.nlm.nih.gov/pubmed/28225073
http://dx.doi.org/10.1038/srep43178