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Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis

The discovery of novel antigens is an essential requirement in devising new diagnostics or vaccines for use in control programmes against human tuberculosis (TB) and bovine tuberculosis (bTB). Identification of potential epitopes recognised by CD4(+) T cells requires prediction of peptide binding to...

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Detalles Bibliográficos
Autores principales: Farrell, Damien, Jones, Gareth, Pirson, Christopher, Malone, Kerri, Rue-Albrecht, Kevin, Chubb, Anthony J., Vordermeier, Martin, Gordon, Stephen V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320590/
https://www.ncbi.nlm.nih.gov/pubmed/28348866
http://dx.doi.org/10.1099/mgen.0.000071