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Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis
The discovery of novel antigens is an essential requirement in devising new diagnostics or vaccines for use in control programmes against human tuberculosis (TB) and bovine tuberculosis (bTB). Identification of potential epitopes recognised by CD4(+) T cells requires prediction of peptide binding to...
Autores principales: | Farrell, Damien, Jones, Gareth, Pirson, Christopher, Malone, Kerri, Rue-Albrecht, Kevin, Chubb, Anthony J., Vordermeier, Martin, Gordon, Stephen V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320590/ https://www.ncbi.nlm.nih.gov/pubmed/28348866 http://dx.doi.org/10.1099/mgen.0.000071 |
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