Cargando…
IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling
BACKGROUND: The IRE1α-XBP1 pathway is the most conserved branch of the unfolded protein response pathways, which are activated during endoplasmic reticulum (ER) stress caused by the accumulation of unfolded/misfolded proteins in the ER lumen. The IRE1α-XBP1 pathway plays a critical role in various c...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320675/ https://www.ncbi.nlm.nih.gov/pubmed/28222747 http://dx.doi.org/10.1186/s12967-017-1147-2 |