The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma

BACKGROUND: HPV infection causes cervical cancer, mediated in part by the degradation of Scribble via the HPV E6 oncoprotein. Recently, Scribble has been shown to be an important regulator of the Hippo signaling cascade. Deregulation of the Hippo pathway induces an abnormal cellular transformation,...

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Detalles Bibliográficos
Autores principales: Alzahrani, Faisal, Clattenburg, Leanne, Muruganandan, Shanmugam, Bullock, Martin, MacIsaac, Kaitlyn, Wigerius, Michael, Williams, Blair A., Graham, M. Elise R., Rigby, Matthew H., Trites, Jonathan R. B., Taylor, S. Mark, Sinal, Christopher J., Fawcett, James P., Hart, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320711/
https://www.ncbi.nlm.nih.gov/pubmed/28222762
http://dx.doi.org/10.1186/s40463-017-0187-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320711/
https://www.ncbi.nlm.nih.gov/pubmed/28222762
http://dx.doi.org/10.1186/s40463-017-0187-1

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