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Mechanism of transcription-coupled DNA modification recognition

As a key enzyme for gene expression, RNA polymerase II (pol II) reads along the DNA template and catalyzes accurate mRNA synthesis during transcription. On the other hand, genomic DNA is under constant attack by endogenous and environmental stresses. These attack cause many DNA lesions. Pol II funct...

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Detalles Bibliográficos
Autores principales: Shin, Ji Hyun, Xu, Liang, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320713/
https://www.ncbi.nlm.nih.gov/pubmed/28239446
http://dx.doi.org/10.1186/s13578-016-0133-3