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Knockdown of SLC41A1 magnesium transporter promotes mineralization and attenuates magnesium inhibition during osteogenesis of mesenchymal stromal cells

BACKGROUND: Magnesium is essential for numerous physiological functions. Magnesium exists mostly in bone and the amount is dynamically regulated by skeletal remodeling. Accelerating bone mass loss occurs when magnesium intake is insufficient; whereas high magnesium could lead to mineralization defec...

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Detalles Bibliográficos
Autores principales: Tsao, Yu-Tzu, Shih, Ya-Yi, Liu, Yu-An, Liu, Yi-Shiuan, Lee, Oscar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320718/
https://www.ncbi.nlm.nih.gov/pubmed/28222767
http://dx.doi.org/10.1186/s13287-017-0497-2