High fat diet dysregulates microRNA-17-5p and triggers retinal inflammation: Role of endoplasmic-reticulum-stress

AIM: To elucidate how high diet-induced endoplasmic reticulum-stress upregulates thioredoxin interacting protein expression in Müller cells leading to retinal inflammation. METHODS: Male C57Bl/J mice were fed either normal diet or 60% high fat diet for 4-8 wk. During the 4 wk study, mice received ph...

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Detalles Bibliográficos
Autores principales: Coucha, Maha, Mohamed, Islam N, Elshaer, Sally L, Mbata, Osinakachuk, Bartasis, Megan L, El-Remessy, Azza B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320749/
https://www.ncbi.nlm.nih.gov/pubmed/28265343
http://dx.doi.org/10.4239/wjd.v8.i2.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320749/
https://www.ncbi.nlm.nih.gov/pubmed/28265343
http://dx.doi.org/10.4239/wjd.v8.i2.56

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