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Maintenance of genome stability by Fanconi anemia proteins

Persistent dysregulation of the DNA damage response and repair in cells causes genomic instability. The resulting genetic changes permit alterations in growth and proliferation observed in virtually all cancers. However, an unstable genome can serve as a double-edged sword by providing survival adva...

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Detalles Bibliográficos
Autores principales: Palovcak, Anna, Liu, Wenjun, Yuan, Fenghua, Zhang, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320776/
https://www.ncbi.nlm.nih.gov/pubmed/28239445
http://dx.doi.org/10.1186/s13578-016-0134-2