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Coupling gene regulatory patterns to bioprocess conditions to optimize synthetic metabolic modules for improved sesquiterpene production in yeast

BACKGROUND: Assembly of heterologous metabolic pathways is commonly required to generate microbial cell factories for industrial production of both commodity chemicals (including biofuels) and high-value chemicals. Promoter-mediated transcriptional regulation coordinates the expression of the indivi...

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Detalles Bibliográficos
Autores principales: Peng, Bingyin, Plan, Manuel R., Carpenter, Alexander, Nielsen, Lars K., Vickers, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320780/
https://www.ncbi.nlm.nih.gov/pubmed/28239415
http://dx.doi.org/10.1186/s13068-017-0728-x