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UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity

Doxorubicin (DOX) is an effective chemotherapeutic drug in the treatment of various types of cancers. However, its clinical application has been largely limited by potential development of cardiotoxicity. Previously we have shown that ultra-violet radiation resistance-associated gene (UVRAG), an aut...

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Detalles Bibliográficos
Autores principales: An, Lin, Hu, Xiao-wen, Zhang, Shasha, Hu, Xiaowen, Song, Zongpei, Naz, Amber, Zi, Zhenguo, Wu, Jian, Li, Can, Zou, Yunzeng, He, Lin, Zhu, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320807/
https://www.ncbi.nlm.nih.gov/pubmed/28225086
http://dx.doi.org/10.1038/srep43251