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Identification of potential leads against 4-hydroxytetrahydrodipicolinate synthase from Mycobacterium tuberculosis

4-hydroxy-tetrahydrodipicolinate synthase (DHDPS) is an important enzyme needed for the biosynthesis of lysine and many more key metabolites in Mycobacterium tuberculosis (Mtb). Inhibition of DHDPS is supposed to a promising therapeutic target due to its specific role in sporulation, cross-linking o...

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Detalles Bibliográficos
Autores principales: Rehman, Ajijur, Akhtar, Salman, Siddiqui, Mohd Haris, Sayeed, Usman, Ahmad, Syed Sayeed, Arif, Jamal M., Khan, M. Kalim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320922/
https://www.ncbi.nlm.nih.gov/pubmed/28293071
http://dx.doi.org/10.6026/97320630012400