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Identification of potential leads against 4-hydroxytetrahydrodipicolinate synthase from Mycobacterium tuberculosis
4-hydroxy-tetrahydrodipicolinate synthase (DHDPS) is an important enzyme needed for the biosynthesis of lysine and many more key metabolites in Mycobacterium tuberculosis (Mtb). Inhibition of DHDPS is supposed to a promising therapeutic target due to its specific role in sporulation, cross-linking o...
Autores principales: | Rehman, Ajijur, Akhtar, Salman, Siddiqui, Mohd Haris, Sayeed, Usman, Ahmad, Syed Sayeed, Arif, Jamal M., Khan, M. Kalim A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320922/ https://www.ncbi.nlm.nih.gov/pubmed/28293071 http://dx.doi.org/10.6026/97320630012400 |
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