Novel aromatase inhibitors selection using induced fit docking and extra precision methods: Potential clinical use in ER-alpha-positive breast cancer

Aromatase (CYP19A1) the key enzyme of estrogen biosynthesis, is often deregulated in breast cancer patients. It catalyzes the conversion of androgen to estrogen, thus responsible for production of estrogen in human body. However, it causes over-production of estrogen which eventually leads to prolif...

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Detalles Bibliográficos
Autores principales: Kumavath, Ranjith, Azad, Manan, Devarapalli, Pratap, Tiwari, Sandeep, Kar, Shreya, Barh, Debmalya, Azevedo, Vasco, Kumar, Alan Prem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2016
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320928/
https://www.ncbi.nlm.nih.gov/pubmed/28293075
http://dx.doi.org/10.6026/97320630012324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320928/
https://www.ncbi.nlm.nih.gov/pubmed/28293075
http://dx.doi.org/10.6026/97320630012324

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