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Quantitation of isobaric phosphatidylcholine species in human plasma using a hybrid quadrupole linear ion-trap mass spectrometer

Phosphatidylcholine (PC) species in human plasma are used as biomarkers of disease. PC biomarkers are often limited by the inability to separate isobaric PCs. In this work, we developed a targeted shotgun approach for analysis of isobaric and isomeric PCs. This approach is comprised of two MS method...

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Detalles Bibliográficos
Autores principales: Zacek, Petr, Bukowski, Michael, Rosenberger, Thad A., Picklo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321225/
https://www.ncbi.nlm.nih.gov/pubmed/27688258
http://dx.doi.org/10.1194/jlr.D070656