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Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease

BACKGROUND: Non-human primates have been shown to be useful models for Chagas disease. We previously reported that natural T. cruzi infection of cynomolgus macaques triggers clinical features and immunophenotypic changes of peripheral blood leukocytes resembling those observed in human Chagas diseas...

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Detalles Bibliográficos
Autores principales: Vitelli-Avelar, Danielle Marquete, Sathler-Avelar, Renato, Mattoso-Barbosa, Armanda Moreira, Gouin, Nicolas, Perdigão-de-Oliveira, Marcelo, Valério-dos-Reis, Leydiane, Costa, Ronaldo Peres, Elói-Santos, Silvana Maria, Gomes, Matheus de Souza, do Amaral, Laurence Rodrigues, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Dick, Edward J., Hubbard, Gene B., VandeBerg, Jane F., VandeBerg, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321273/
https://www.ncbi.nlm.nih.gov/pubmed/28225764
http://dx.doi.org/10.1371/journal.pntd.0005233