Cargando…
Cynomolgus macaques naturally infected with Trypanosoma cruzi-I exhibit an overall mixed pro-inflammatory/modulated cytokine signature characteristic of human Chagas disease
BACKGROUND: Non-human primates have been shown to be useful models for Chagas disease. We previously reported that natural T. cruzi infection of cynomolgus macaques triggers clinical features and immunophenotypic changes of peripheral blood leukocytes resembling those observed in human Chagas diseas...
Autores principales: | Vitelli-Avelar, Danielle Marquete, Sathler-Avelar, Renato, Mattoso-Barbosa, Armanda Moreira, Gouin, Nicolas, Perdigão-de-Oliveira, Marcelo, Valério-dos-Reis, Leydiane, Costa, Ronaldo Peres, Elói-Santos, Silvana Maria, Gomes, Matheus de Souza, do Amaral, Laurence Rodrigues, Teixeira-Carvalho, Andréa, Martins-Filho, Olindo Assis, Dick, Edward J., Hubbard, Gene B., VandeBerg, Jane F., VandeBerg, John L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321273/ https://www.ncbi.nlm.nih.gov/pubmed/28225764 http://dx.doi.org/10.1371/journal.pntd.0005233 |
Ejemplares similares
-
Phenotypic Features of Circulating Leukocytes from Non-human Primates Naturally Infected with Trypanosoma cruzi Resemble the Major Immunological Findings Observed in Human Chagas Disease
por: Sathler-Avelar, Renato, et al.
Publicado: (2016) -
Phenotypic and Functional Signatures of Peripheral Blood and Spleen Compartments of Cynomolgus Macaques Infected With T. cruzi: Associations With Cardiac Histopathological Characteristics
por: Sathler-Avelar, Renato, et al.
Publicado: (2021) -
Blood leukocytes from benznidazole-treated indeterminate chagas disease patients display an overall type-1-modulated cytokine profile upon short-term in vitro stimulation with trypanosoma cruzi antigens
por: Sathler-Avelar, Renato, et al.
Publicado: (2012) -
Regulatory T Cells Phenotype in Different Clinical Forms of Chagas' Disease
por: de Araújo, Fernanda Fortes, et al.
Publicado: (2011) -
Differential Expression of Intestinal Genes in Opossums with High and Low Responses to Dietary Cholesterol
por: Chan, Jeannie, et al.
Publicado: (2010)